Until recently, only apolipoprotein E (APOE) polymorphisms have been found to co

Question

Until recently, only apolipoprotein E (APOE) polymorphisms have been found to correlate with late-onset (nonfamilial) Alzheimer disease (AD); however, these account for less than 50% of the VG. New GWA studies have found a chromosome 12 risk locus. What method will likely be used by AD researchers going forward?

Until recently, only apolipoprotein E (APOE) polymorphisms have been found to correlate with late-onset (nonfamilial) Alzheimer disease (AD); however, these account for less than 50% of the VG. New GWA studies have found a chromosome 12 risk locus. What method will likely be used by AD researchers going forward?

analysis of genotypes of a large number of AD patients who have none of the expected APOE alleles sequencing of candidate genes on chromosome 12 and search for sequence similarity association of APOE alleles with chromosome 12 SNPs assessment of chromosome 12 for areas of linkage disequilibrium for AD genotyping of a large cohort of AD patients and matched controls using a microchip

Explanation / Answer

genotyping of a large cohort of AD patients and matched controls using a microchip

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