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4. After a heart transplant, there is no direct connection between the nervous s

ID: 48400 • Letter: 4

Question

4. After a heart transplant, there is no direct connection between the nervous system and the heart. However, the cardiac output of patients with heart transplants can vary in response to changes in metabolic demand (for example, cardiac output will increase during exercise).

How could this be possible? Explain.

Would you expect this regulation of cardiac output to be as efficient as in an individual who has not had a heart transplant (someone who still has a direct connection between the nervous system and the heart)? Explain why or why not.

Explanation / Answer

At the outset, the cardiac muscle is "myogenic", it means that it possess a rhythmic activity of the cardiac muscles and it doesn

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