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1. Why can’t influenza virus replicate in a cell where the nucleus has been remo

ID: 226996 • Letter: 1

Question

1. Why can’t influenza virus replicate in a cell where the nucleus has been removed? •

2. You lab is researching the Spring fever virus(SpFV) and the debilitating variant SpFV-4 that causes senioritis. Others have identified SpFVas an Influenza virusbut your team’s research results show it may be a new genus tentatively called Procrastinovirus. The following table list properties of SpFVstrains studied in your lab:

PLEASE ANSWER ALL THE QUESTIONS AS BEST AS YOU CAN!!! THANK YOU! :)

Viral function Results for SpFv Virion membrane glycoproteins Two major proteins, one with hemagglutinin activity and the other with neuraminidase activity Matrix proteins in virion One matrix protein Genome segments Eight single-stranded RNA molecules Nuclear location, with cap scavenging from host mRNA Viral mRNA synthesis precursors and RNA splicing to produce some species of viral mRNA Nonstructural (NS) proteins in Three NS proteins, two encoded by RNA segment 8 and one infected cells encoded by RNA segment 6 Site of infection Generalized neuromuscular locations, ultimately targeting higher neural functions associated with and memory motivation (a) Which features of SpFV are similar to Influenza virus? (b) which features are different from Influenza virus? (c) Which viral proteins do you predict will be different between SpFV and SpFV-4? (d) What might account for the ability of SpFV-4 strain to produce senioritis?

Explanation / Answer

1.

2.

a) Similar features:

b)

c)

d)