Based on the example below (and not really knowing anything about these pathways

Question

Based on the example below (and not really knowing anything about these pathways and chemicals what is the: 1. What is the direct effect of a drop in blood pressure: 2. What is the indirect cause of an increase in angiotensin 1 levels? Scenario: a. A drop in blood pressure causes the kidney to secrete renin b. Renin causes the conversion of a plasma protein to angiotensin I. c. Conversion of angiotensin I to angiotensin II is caused by an enzyme in the lungs d. Angiotensin II causes an increase in aldosterone secretion from the adrenals The plasma membrane is considered hydrophobic. Will a polar molecule or non-polar molecule be more likely to cross freely through the plasma membrane, why? (ex. salt (NaCl) or (ex: oils, fat based molecules (steroid) a. Polar, because it's water loving b. Polar, because it's water hating c. Non-polar, because it's water loving d. Non-polar, because it's water hating Proteins have polar regions, will it freely cross the membrane? a. Yes b. No c. Maybe Fat is non-polar, will it freely cross the membrane? a. Yes b. No c. Maybe

Explanation / Answer

Ans.1.) A drop in the arterial blood pressure causes the conversion of angiotensin I to angiotensin II by angiotensin-converting enzyme (ACE), found primarily in lung.

Indirect cause of increase in angiotensin I is due to production of rennin (an enzyme) which is responsible for the synthesis of angiotensin I.

2.) “d” Non-polar molecules can easily cross the plasma membrane.

3.) “a” Polar molecules can easily cross the plasma membrane.

4.) “a” Yes, fat could freely cross the membrane.

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