A gene encodes a protein that carries out two functions. The following series of

Question

A gene encodes a protein that carries out two functions. The following series of events occurs: This gene becomes duplicated. The duplicated genes subfunctionalize such that each paralog retains one of the two functions. One paralog acquires an additional new function. A speciation event occurs, and the two paralogs in one species diverge in sequence from the two paralogs in the other species. However, the genes maintain the same functions.

Discuss the functional impact of nucleotide substitutions that are likely to sweep through the population at each stage after the duplication event. Explain why certain types of mutations are likely to become fixed at each stage. What effect would these mutations have on fitness?

Explanation / Answer

At the stage where genes retains one function each then this means that there was not amino acid sequence conservation but the nucleotide substitution was made with a substitute that was functionally equivalent when we consider the physicochemical properties.

Sometimes certain mutations are no longer segregating but become fixed because in the population every individual has that mutation in the genes.

In the given case the mutations will not have any major effect on the fitness and will perform in normal manner as the genes have maintained the same functions even after the series of events mentioned.

Related Questions

Navigate

• Browse (All)
• Browse A
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.