Dwain accidentally washed off the labels off of his three drugs that he was usin

Question

Dwain accidentally washed off the labels off of his three drugs that he was using to treat cells. One of the drugs inhibited myosin, one of them inhibited kinesin, and one of them inhibited dynein. Dwain picked one of the drugs at random and used it on some of his immune cells that normally secrete antibodies. When he analyzed the cells he saw that the cleavage furrow seemed to be working fine, the Golgi were forming fine, but the ER was not very spread out in the cells and the cells were unable to secrete any antibodies. Which drug had he likely used?

Explanation / Answer

Inhibition of myosin disrupts the formation of cleavage furrow during cytokinesis and the inhibition of dynenin disrupts the retrograde transport and leads to a collapse of the Golgi apparatus into the Endoplasmic reticulum. Since, the treatment with the random drug did not perturb the cleavage furrow formation or the compromise the structural integrity of Golgi, the drug must be an inhibitor of kinesin. This is also supported by the inability of the cells to secrete antibodies (as the anterograde transport is disrupted by the inhibition of kinesin) and the damaged structural integrity of the Endoplasmic reticulum.

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