DNA, RNA, and Snorks You will examine the DNA sequence of a fictitious organism
ID: 79493 • Letter: D
Question
DNA, RNA, and Snorks You will examine the DNA sequence of a fictitious organism - the Snork. Snorks only have one chromosome with ten genes on it. Your job is to analyze the genes of its DNA and determine what traits the organism has and then sketch the organism (You can be creative here). For simplicity, the gene sequences are much smaller than real gene sequences found in living organisms. Each gene has two versions that result in a different trait being expressed in the snork.Each of the 10 genes is separated by vertical lines. Use the wheel or the table on the following page to determine which amino acid each codon (set of 3 letters) codes for. Use the table on the 3rd page to identify which characteristic is being coded for given the sequence of amino acids.
Snapple Snork | GUC AGC CUU | GUU CCC ACA GAA AAA | CUC UUA AGU GCG | GUU GCG GCU | | CAC AUU | UCU CCC GUA | GAU AUU CCC CCC CCC ACC | |GAU GAC GAC GCA | UUC UUU GGG | CGC CGG GAC |
| Genes Amino Acid Sequence Description Gene 1 - body covering val - ser - leu hairless val - ser - lys hairy Gene 2 - body style tyr - pro - glu - glu - lys plump val - pro - thr - glu - lys skinny Gene 3 - legs leu - leu - leu - pro 3 legged leu - leu - ser - ala 2 legged Gene 4 - head shape ala - val - val round head val - ala - ala square head Gene 5 - tails his - ile tail his - his no tail Gene 6 - body pigment ser - pro - val blue pigment (hair/skin) val - phe - tyr red pigment (hair/skin) Gene 7 - eyes asp - ile - leu - leu - pro - thre small slanted eyes asp - ile - pro - pro - pro - thre large round eyes Gene 8 - mouth val - asp - asp - ala circular mouth asp - asp - asp - ala rectangular mouth Gene 9 - ears phe - ser - gly pointed standing-up ears phe - phe - gly rounded floppy ears Gene 10 - arms arg - tyr - cys - lys long spaghetti like arms arg - arg - asp - thre short stumpy arms
aUCAGiuee UC Vale 1 G te Serne U A ACUIG ACU Table 12.1 The Genetic Code* Second position UAL Tyr UCC UCU UCU UUC Phe The UCC UAC Tyr UCC Cysc UCA Ser UAA Stop UGA Stop A UUG Leu Leu UCG UAG Stop UCC Trp CCA Pro CAC) His CCU CAU) His CCC Arg C CUU }His CUA/ CC CCC )Pro CAA, cin culA CUG cuc ACA /Thr AAC) Asn AGU AAU) Asn ACC A AUU ACC Ser ACC )Thr MA) Lys ACG AUC ne Met/ ACA AAA } Lys AGA }Arg e AUG Met/ ACC GCA /Ala GAC) Asp CGU GAU) Asp acay G GUU ) GUC, Val CCA GCC)Ala GAA Glu GGG GAG] Clu CCA /Cly GUA/ Val CUG ) "Exceptions to the genetic code are sporadically found annig various species. For example, ALIA uoylysod pu!ELL UCAC UCAG UCAG UCAG Arg Ser Arg aUCAG St St 13 UO) {‘|A-uic UM uic cau cic CIA ac ANI MC MA MG } CIA ac c| U anyone AAAA uouso's sit-I
Explanation / Answer
Steps in solving the problem;
First we need to find the amino acid sequence encoded by all the 10 genes. Gene sequences were listed. Use genetic code to find which amino acid is coded by the triplet codons in the gene sequences. E should use the information in table 12.1 to find amino acids.
The second step is to identify the phenotype for each protein sequence obtained in the first step. Phenotype information is given in the last part of the question. We should pick up the appropriate phenotype (description) for the protein sequence we obtained.
Solution:
Here is the list of sequences of all the genes in the organism. Protein sequences coded by each gene are shown in bold font. Phenotype of the gene is written against it and is underlined.
GUC AGC CUU Val-Ser-Leu Hairless
GUU CCC ACA GAA AAA Val-Pro-Thr-Glu-Lys Skinny
CUC UUA AGU GCG Leu-Leu-Ser-Ala 2 legged
GUU GCG GCU Val-Ala-Ala square head
CAC AUU His-Ile has tail
UCU CCC GUA Ser-Pro-Val skin color blue.
GAU AUU CCC CCC CCC ACC Asp-Ile-Pro-Pro-Pro-Thr Large round eyes
GAU GAC GAC GCA Asp-Asp-Asp-Ala Rectangular mouth
UUC UUU GGG Phe-Phe-Gly rounded floppy years
CGC CGG GAC Arg-Arg-Asp Short stumpy arms
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