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Based on the information in the figures, which of the following statements about

ID: 572181 • Letter: B

Question

Based on the information in the figures, which of the following statements about glutamate are TRUE?

A. At pH 2.19 there are equal amounts of Form 1 and Form 2.

B. The alpha carboxyl group is half dissociated at pH 9.67.

C. Glutamate would be a good buffer at pH values near 2.2 and 9.7.

D. Glutamate has biological importance because the pKa of its side chain is close to physiological pH.

E. Glutamate's pI is beween 2.19 mad 4.25.

F. Glutamate's pI is between 4.25 and 9.67.

G. Glutamate is an aromatic amino acid.

10 Glutamate 2 9.67 8 6 pH 4.25 4 2 I 2.19 1.0 2.0 3.0

Explanation / Answer

Biochemistry

From the titration curves and pKa values from the pH at half-equivalence points in the titration curve shown above

The true statements here would be,

A. at pH 2.19, there are equal amounts of form 1 and form 2.

C. Glutamate would be a good buffer at pH values near 2.2 and 9.7.

E. Glutamate pI is between 2.19 and 4.25

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