A woman who is homozygous recessive for a mutation that results in deafness marr
ID: 55559 • Letter: A
Question
A woman who is homozygous recessive for a mutation that results in deafness marries an unrelated man who is also deaf because he is homozygous for a recessive mutation. They have a child whose hearing is normal. Explain how this can happen. What genetic principle does this situation exemplify? The pedigree illustrated here shows individual II-2 affected with a rare recessive trait. Let A and represent the dominant and recessive alleles. What is the genotype of II-2? What are the genotypes of 1-1 and 1-2? What are the possible genotypes of II-1 and II-3? What is the probability that II-3 is a heterozygous carrier of the a allele? In Problem 2.8, what is the probability that both II-1 and II-3 are carriers? That neither is a carrier? That at least one is a carrier?Explanation / Answer
1. If the both the parents are carriers Aa X Aa The genotypes will be AA. Aa. Aa, aa
The probability that both II1 and II 3 are carrier is 1/4
The probability that neither is carrier is 1/4
The probability that at least one is carrier is 1/2
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