1. What would happen if we tried to estimate species relationships using paralog

Question

1. What would happen if we tried to estimate species relationships using paralogous gene copies?
2. If you had short orthologous gene sequence from a few different species, is there a different way you could determine gene sequence? 1. What would happen if we tried to estimate species relationships using paralogous gene copies?
2. If you had short orthologous gene sequence from a few different species, is there a different way you could determine gene sequence? 1. What would happen if we tried to estimate species relationships using paralogous gene copies?
2. If you had short orthologous gene sequence from a few different species, is there a different way you could determine gene sequence?

Explanation / Answer

1. Paralogous gene copies are the homologous genes that are evolved by duplication. The proteins coded by these genes are identical but differ in function. Whereas orthologs genes are evolved from a common ancestral gene by speciation, the proteins coded by orthologous genes perform same function though they belong to different species. We generally use orthologous gene identity to ascertain species identity because we don't find speciation in paralogous genes and we cannot relate them with this information as they do not reflect the history of speciation. Whereas the history of evolution of orthologous genes reflect the history of speciation and so we can relate them.

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