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DNA polymerase requires a primer and cannot initiate synthesis de novo . What se

ID: 3763 • Letter: D

Question

DNA polymerase requires a primer and cannot initiate synthesisde novo. What serves as a primer for DNAreplication?

A protein with afree OH group

The DNA forms aloop resulting in the formation of double-stranded hairpins at theend of the DNA molecule, and these hairpins serve as primers.

Short fragmentsof RNA complementary to the template strand

Short fragmentsof DNA complementary to the template strand

DNA polymerase requires a primer and cannot initiate synthesisde novo. What serves as a primer for DNAreplication?

A protein with afree OH group

The DNA forms aloop resulting in the formation of double-stranded hairpins at theend of the DNA molecule, and these hairpins serve as primers.

Short fragmentsof RNA complementary to the template strand

Short fragmentsof DNA complementary to the template strand

Explanation / Answer

In most cases of natural DNA replication, the primer for DNAsynthesis and replication is a short strand of RNA (which can bemade de novo) the answer is the third choice