1a. If the concentration of Na++ ions in the interstitial fluid bathing the baso
ID: 3517439 • Letter: 1
Question
1a. If the concentration of Na++ ions in the interstitial fluid bathing the basolateral side of proximal convoluted tubule epithelial cells was somehow doubled, how would that impact glucose reabsorption into proximal tubule epithelial cells from the nephron lumen on an acute timescale? Ignore all possible consequences of this manipulation on any process other than glucose absorption.
a. It would slow reabsorption, because the Na++ concentration gradient needed drive secondary active transport of glucose would be reduced.
b. It would speed reabsorption, because the Na++ concentration gradient needed drive secondary active transport of glucose would be enhanced.
c. There would be little impact of this manipulation on glucose reabsorption.
d. It would speed reabsorption, because more Na++ ions would be available to be contransported with glucose into the epithelial cells.
1b. Solute X is a very small organic molecule present in the blood plasma at approximately 17 mM. The average concentration of solute X in the mature urine that is voided from the body is essentially 0 mM. This difference indicates that:
a. The filtration rate of solute X must be fairly low.
b. The reabsorption rate of solute X must be fairly high.
c. The secretion rate of solute X must be fairly high.
d. The excretion rate of solute X must be fairly high.
Explanation / Answer
Anwer to 1 a.is D.
Glucose is cotransported with sodium ion into the proximal convoluted tubule. So it would speed up glucose reabsorption.
Answer for 1 B is b.
If a substance is not found in urine then that indicates the reabsorption of the same by nephron is high.
Organic solutes are filtered and reabsorbed in nephron the exception being urea.
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