Three s napses occur along e dend te o neuron, as shown in the picture. A the sy

Question

Three s napses occur along e dend te o neuron, as shown in the picture. A the synapses with neurons A and C the oosts apcic n en bra e has l gand ated channels pe eable to both Na and K", whle atthe s naose with neuron here are only and aedchannes 10K" The effect of action potentials (AFs) occuring In neurons A B, and C is measured with an electrode at the intial segment of the postsynaptic neuron. A:let are pairs of experiments In which APs are Induced In one cr more of the three presynaptic neurons. Evaluate which experiment wthin each pair would result in the most posltlve postsynaptic membrane potemtial, and drag that pair to the comect RESULTS box Condition one is more positive both B and C Condiion bu: AP in onty neuran C ont neuren B Conditon bu Cendtian ome AP n onty neuran C

Explanation / Answer

Whereas inhibitory post synaptic potential (IPSP) is caused due to :

So, here out of the given 8 pairs let us assign an arbitrary +1 for an open Na+ channel and a -1 for an open K+ channel. So we can solve for the channels as follows:

Now, we can easily solve for the pairs as to which will produce a more positive deflection, the more positive the value between the pairs the more positive the deflection.

Thus we can find out the more positive deflections between the pairs.

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