A 28-year-old woman has been sick with the flu for the past week, vomiting sever

Question

A 28-year-old woman has been sick with the flu for the past week, vomiting several times every day. She is having a difficult time keeping solids and liquids down, and has become severely dehydrated. After fainting at work, she was taken to a walk-in clinic, where an IV was placed to help rehydrate her. Arterial blood was drawn first, revealing the following: pH of 7.30………(Normal 7.35 – 7.45) pCO2 50 mmHg (partial pressure of carbon dioxide)……………(Normal 40 mm Hg) pO2 55 mmHg   (partial pressure of oxygen)……...……………..(Normal 90-100 mm Hg) Hemoglobin/O2 saturation 45%…….(Normal 94-100%) [HCO3-] 24 meq/L ………..………….(Normal 24 meq/L) First, how would you classify her acid-base disturbance? Secondly, how do you think her kidneys are trying to compensate for the acid-base imbalance?

Explanation / Answer

1.in this case the pataint is in respiratory acidosis condition.because here the ph value is 7.3 and partial pressure of carbon dioxide is 50 mmhg .in respiratory acidosis due to alveolar hypoventilation there is accumulation of carbon dioxide and decrese in blood ph.

2 kideney compesate by retaining bicarbonate from tubular fluid.collecting duct secrete more hydrogen and generate bicarbonatte.

In case of acute conditon intracellular buffering and plasma bicarbonate increase.

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