It is known that the manx allele in cats is an autosomal recessive lethal and is

Question

It is known that the manx allele in cats is an autosomal recessive lethal and is abbreviated "M". The manx allele interferes with normal spinal development, and cats with one copy of the manx allele have no tail (Manx is dominant for the tailless phenotype). A manx homozygote has extreme developmental abnormalities and does not survive. Normal cats have a tail and the normal allele is abbreviated "m". You are studying this trait in a population of wild cats

You observe that in the initial generation (G0), there are:

761 manx (tailless) cats

613 normal cats

You observe that in G1, there are:

386 manx (tailless) cats

547 normal cats.

What is the observed frequency of the M allele in G0?

Use 4 decimal places in your answer.

Explanation / Answer

As per the given question the population of G0 are as follows:

Normal cats: 613 (mm)

manx tailless cats: 761 (Mm)

total = 1374

Now By, Hardy

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