Botox for excessive sweating. Hyperhidrosis is a stressful medical condition cha
ID: 3220375 • Letter: B
Question
Botox for excessive sweating. Hyperhidrosis is a stressful medical condition characterized by chronic excessive sweating. Primary hyperhidrosis is inherited and typically starts during adolescence. Botox was approved for treatment of hyperhidrosis in adults in 2004. A clinical trial examined the effectiveness of botox for excessive armpit sweating in teenagers aged 12 to 17 years. Participants received either a Botox injection or a placebo injection (a simple saline solution) and were examined four weeks later to see if their sweating had been reduced by 50% or more. Here are the study’s findings
a) Consider a test for the claim that the proportion of at least 50% reduction in Botox is as common as the Placebo treatment. Which of the following test can be used for the claim _________
a) Z test
b) GOG test
c) Contingency test
d) Both A and C
e) Both A and B
f) Both B and C
g) All A B and C
b) Perform the test for the claim.
Treatment Botox Placebo Total At Least 50% Reduction Yes No 20 44 128 Total 104 108 212Explanation / Answer
a)Perform a contingency for the claim that whether participant received Botox orplacebo injection is independent with the result.
H0: Pr(Reduction Yes | Treatment Botox) = Pr(Reduction Yes | Treatment Placebo)
Ha: Pr(Reduction Yes | Treatment Botox) Pr(Reduction Yes | Treatment Placebo)
c) Contingency test
b,
H0: Pr(Reduction Yes | Treatment Botox) = Pr(Reduction Yes | Treatment Placebo)
Ha: Pr(Reduction Yes | Treatment Botox) > Pr(Reduction Yes | Treatment Placebo)
Sample Pr(Reduction Yes | Treatment Botox) = 84 / 104 = 0.8077
Sample Pr(Reduction Yes | Treatment Placebo) = 44 / 108 = 0.4074
Sample Pr(Reduction Yes | Treatment Botox) > Sample Pr(Reduction Yes |Treatment Placebo), continue.
P-value < 0.0005 / 2 = 0.00025
P-value < 0.05, so we reject H0, and we have enough evidence that participantsreceived Botox injection is better than placebo injection to treat chronic excessivesweating.
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