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A large medical center’s oncology program reported an increased number of cases

ID: 3004794 • Letter: A

Question

A large medical center’s oncology program reported an increased number of cases of pancreatic cancer during a certain month. The hospital’s epidemiologist decided to research the problem. Tumor registry records were searched to identify all cases of pancreatic cancer during a five-year period; cancer patients were matched with patients treated for other diseases during the same five-year period. All subjects in the study were questioned about lifestyle factors including alcohol, tea, and coffee consumption. The resulting data are as follows:

DATA

Cancer Patients

Other Patients

Men

Women

Men

Women

LIFESTYLE VARIABLE

Alcohol

185

120

270

260

Tea Drinking

140

110

230

225

Coffee Drinking

190

140

270

240

Note:   Total number of male cancer patients = 200.

            Total number of female cancer patients = 150.

            Total number of male patients (other diseases) = 300.

            Total number of female patients (other diseases) = 300.

4. Please calculate the measure of association associated with alcohol drinking in men and describe your results in words?

5. Please calculate the measure of association associated with alcohol drinking in women and describe your results in words?

6. Please calculate the measure of association associated with tea drinking in men and describe your results in words?

7. Please calculate the measure of association associated with tea drinking in women and describe your results in words?

8. Please calculate the measure of association associated with alcohol drinking in men and describe your results in words?

9. Please calculate the measure of association associated with alcohol drinking in women and describe your results in words?  

DATA

Cancer Patients

Other Patients

Men

Women

Men

Women

LIFESTYLE VARIABLE

Alcohol

185

120

270

260

Tea Drinking

140

110

230

225

Coffee Drinking

190

140

270

240

Explanation / Answer

4. measure of assosciation is calculated through odd ratio.

odd of cancer among alcohol consuming man=185/15=x

odd of other disease among alcohol consuming man=270/30=9=y

odd ratio=x/y=1.37

odd ratio is greater than 1, it implies alcohol consume rhas higher chance of cancer then any other disease.

5.

odd of cancer among alcohol consuming women=120/30=4=x

odd of other disease among alcohol consuming man=260/40=y

odd ratio=x/y=0.61

odd ratio is less than 1, it implies alcohol consume has higher chance of other disease than cancer among women.

all parts do it like this..

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