A large medical center’s oncology program reported an increased number of cases
ID: 3004936 • Letter: A
Question
A large medical center’s oncology program reported an increased number of cases of pancreatic cancer during a certain month. The hospital’s epidemiologist decided to research the problem. Tumor registry records were searched to identify all cases of pancreatic cancer during a five-year period; cancer patients were matched with patients treated for other diseases during the same five-year period. All subjects in the study were questioned about lifestyle factors including alcohol, tea, and coffee consumption. The resulting data are as follows:
DATA
Cancer Patients
Other Patients
Men
Women
Men
Women
LIFESTYLE VARIABLE
Alcohol
185
120
270
260
Tea Drinking
140
110
230
225
Coffee Drinking
190
140
270
240
Note: Total number of male cancer patients = 200.
Total number of female cancer patients = 150.
Total number of male patients (other diseases) = 300.
Total number of female patients (other diseases) = 300.
5. Please calculate the measure of association associated with alcohol drinking in women and describe your results in words? (7.5 points)
6. Please calculate the measure of association associated with tea drinking in men and describe your results in words? (7.5 points)
7. Please calculate the measure of association associated with tea drinking in women and describe your results in words? (7.5 points)
8. Please calculate the measure of association associated with coffee drinking in men and describe your results in words? (7.5 points)
9. Please calculate the measure of association associated with coffee drinking in women and describe your results in words? (7.5 points)
10. Which factor has the strongest association with cancer for both men and women? (5 points)
A. Alcohol consumption
B. Tea drinking
C. Coffee drinking
D. The factors show no variation in the association.
E. Not enough information to determine
DATA
Cancer Patients
Other Patients
Men
Women
Men
Women
LIFESTYLE VARIABLE
Alcohol
185
120
270
260
Tea Drinking
140
110
230
225
Coffee Drinking
190
140
270
240
Explanation / Answer
5. odd of cancer among alcoholic women=120/(150-120)=120/30=4
odd of other disease among alcoholic women=260/(300-260)=260/40=6.5
measure of assosication= 4/6.5=0.615
6.odd of cancer among tea drinking men=140/60=
odd of other disease among tea drinking man=230/70
measure of assosication= (140/60)/(230/70)=0.71
7. odd of cancer among tea drinking women=110/40
odd of other disease among tea drinking women=225/75
measure of assosication=( 110/40)/(225/75)=0.92
8. odd of cancer among coffee man=190/10=19
odd of other disease among coffee men=270/30=9
measure of assosication= 2.11
9.odd of cancer among coffee women=140/10=14
odd of other disease among coffee women=240/60=4
measure of assosication=14/4=3.5
10. measure of assosciation is highest in coffee for both men and woemn. thus it has strongest assosciation with cancer.
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