8 Your patient is the propositus (arrow) on the pedigree. You can see that diabe

Question

8 Your patient is the propositus (arrow) on the pedigree. You can see that diabetes does run in the family. The individuals with lines through the boxes are pre-diabetic. The gel below the pedigree shows PCR products within the insulin gene. Two bands represent two different alleles and one band represents an individual with two identical alleles. Given this information, which allele is associated with the mutation? Why (4 points) VI. VII. In generation three, you see that there are 4 people with the same genotype but different phenotypes. How can you explain this? Include both environmental and genetic reasons (4 points) If your patient married an individual with a genotype identical to that of the "C" lane, what is the chance that their child would have diabetes? (2 points, show work!) VIII.

Explanation / Answer

Ans-vi- allele where two bands are closely situated is associated with the disease as it is clearly indicated in the gel pictures where C allele is present in every sample but M allele is present only in the patients suffering from the disease.

Ans-vii- environmental conditions are also reaponsible for some disease to occur. In case of diabetes stress and other stress related factors aid on the diabetes so due to association of these factors will be responsible for the differences in the phenotype even after same genotype.

Ans-viii- C is condition where the alleles are same and no diabetes if some one marry with C then there will be

CC are normal and MC are patients so there will be 2/4 i.e. 50% chances .

M C C MC CC C MC CC

Related Questions

Navigate

• Browse (All)
• Browse 8
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.