8 Question 3(15 points): Suppose there are 500 pairs of pregnant women who parti

Question

8 Question 3(15 points): Suppose there are 500 pairs of pregnant women who participate in a prematurity study and are paired in such a way that the body weights of the 2 women in a pair are within 5 lb of each other. One of the 2 women is given a placebo and the other drug A to see if drug A has an effect in preventing prematurity. Suppose that in 30 pairs of women, both women in a pair have a premature child, in 420 pairs of women, both women have a normal child; in 35 pairs of women, the woman taking drug A has a normal child and the woman taking the placebo has a premature child; in 15 pairs of women, the woman taking drug A has a premature child and the woman taking the placebo has a normal child Assess the statistical significance of these results. 07:

Explanation / Answer

Answer:

This is a paired data.

McNemar's test is a statistical test used on paired nominal data.

Ho: There is no effect

H1: There is an effect

Placebo

Premature

Normal

Total

Premature

30

15

45

Drug A

Normal

35

420

455

Total

65

435

500

Chi square = (B-C)2 / (B+C)

= (35-15)^2/( 35+15)

=8.0

DF=1

Calculated chi square =8.0 is < 3.841, critical chi square at 0.05 level of significance.

Ho is rejected.

There is statistical significance in treatment with respect to prematurity.

Placebo

Premature

Normal

Total

Premature

30

15

45

Drug A

Normal

35

420

455

Total

65

435

500

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