Toxicology question. What is the consideration and preference given by toxicolog

Question

Toxicology question.

What is the consideration and preference given by toxicologist in the selection of drug safety index?

a. The LD50/ED50 is very easy to calculate and will require more data from the dose-response studies to be incorporated – like thresholds, slopes of the curves as well as the maximal effects possible.

b. Margin of safety is important to be used by the FDA as well as the EPA in the regulatory processes in both drug and chemical manufacturing processes

c. The MOS considers the lethality of the drug to 1% versus the effectiveness to 99% of the population while the TI uses the 50% lethality versus 50% effectiveness in the population. It considers the TI riskier to the safety of the populace.

d. All the above

Explanation / Answer

the consideration and preference given by toxicologist in the selection of drug safety index is:

Answer) all of the above

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