John and Mary both have achondroplastic dwarfism with 90% penetrance. Mary is in
ID: 259185 • Letter: J
Question
John and Mary both have achondroplastic dwarfism with 90% penetrance. Mary is in labor, and the baby will be born in a few hours. Which of the following is WRONG?
Both John and Mary are certainly heterozygous
There is a 25% chance that this baby is unaffected.
Both John and Mary may have unaffected parents.
It is possible that this baby is unaffected but he/she will have an affected child in the future.
John is affected with a Y-linked disorder. What portion of his sperm will carry the normal allele of the corresponding gene?
None
25%
50%
75%
100%
A.Both John and Mary are certainly heterozygous
B.There is a 25% chance that this baby is unaffected.
C.Both John and Mary may have unaffected parents.
D.It is possible that this baby is unaffected but he/she will have an affected child in the future.
Explanation / Answer
The correct answer is option D that is it is possible that this baby is unaffected but he/she will have an affected child in the future because the disease is inherited in an autosomal dominant fashion and if the child is Unaffected then it can't have affected child in case of dominant disease.
2) The correct answer is option C that is 50% of the sperm with carry the normal allele of the corresponding gene having Y linked disorder.
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