A prospective cohort study was conducted to determine the risk of heart attack a

Question

A prospective cohort study was conducted to determine the risk of heart attack among men with varying levels of baldness. Third-year residents in dermatology conducted visual baldness assessments at the start of the study (which was before any heart attacks had occurred). Four levels of baldness were coded: none, minimal, moderate, and severe. The follow-up rate for this study was 100%. Which of the following types of bias were avoided in this study? (Choose all that apply)

a. Recall bias of the exposure information.

b. Differential misclassification of the exposure.

c. Non-differential misclassification of the exposure.

d. Selection bias due to follow up.

2. A case-control study was conducted to determine if using any antihistamines around the time of conception increased the risk of birth defects in the offspring.  No personal interviews were conducted regarding the subjects’ antihistamine use. Instead, women were considered exposed if computerized pharmacy records from their health maintenance organization indicated that they had filled at least one prescription for antihistamines within 500 days before the birth of the child.

a)For which type of information bias is this data collection method susceptible?

b)Which type of information bias is this data collection method least susceptible to?

Explanation / Answer

Question 1 :

1- recall bias is avoided because the subjects dont have to remember about the exposure as this is cohort study.

2- Differential bias of misclassification is not possible here since exposure is misclassified related to disease , since here disease is not present , it wont occur

4- Selection bias due to follow up since 100 percent follow up.

Question 2:

A- Most susceptible biasing here is selection biasing since interviewer can case and controls according to his own choice.

B- Least susceptible is recall bias since the interviewing is not done at all .

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