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MICROBIOLOGY What are the functions of the spleen? Explain the process & stages

ID: 170714 • Letter: M

Question

MICROBIOLOGY

What are the functions of the spleen?

Explain the process & stages of inflammation:

What is the function of each of the following chemicals and where are they made?

Histamine:

Heparin:

Define “chemotaxis”:

What is the function of “pyrogen” substance in the inflammatory process?

Cite 2 white blood cells responsible for phagocytosis of the germs:

.

.

What is the 3rd line of defense against germs in our body?

Define “immunoglobulin”: and give 3 types of immunoglobulins and their function

Definition:

Example1:

Example 2:

Example 3:

Explanation / Answer

Function of Spleen

Two areas of spleen have different major function.

Red pulp area is responsible for mechanical filtration of RBC. While white pulp region is responsible for active immune response through humoral and cell-mediated pathways.

There are some minor functions too.

Spleen helps in production of opsonins, properdin, and tuftsin.

Until the fifth month of gestation spleen is the site of creation of RBC.

Spleen acts as storage of red blood cells, lymphocytes and other formed elements.