A survey of genetic disorders in a certain country found the probability of carr

Question

A survey of genetic disorders in a certain country found the probability of carrying genes for some disorders as follows: sickle cell anemia myotonic muscular dystrophy Huntington's disease geneticslabititis cystic fibrosis hemophilia other none 0.57% 0.20% 0.25% 06T% 0. 50% 0.21% 5% 92.60% | When a survey was done on a sample of the population within the country (with the assumption that this will represent the whole population), the following numbers were observed sickle cell anemia myotonic muscular dystrophy Huntington's disease geneticslabititis cystic fibrosis hemophilia other none 17 10 20 7 13 120 2808 a) State a hypothesis and then test statistically for goodness of fit between the two datasets. Give all the information necessary regarding the support of your hypothesis If all disorders were grouped together and the assumption is that 6% of the population is expected to carry a gene for some genetic disorder, will the observed values fit with the expected? b)

Explanation / Answer

ans 1..the hypothesis is that the result of frequency of an allele from a sample if non biased random population can be reflected back to the whole population.

for example here in whole population,sickel cell anemia trait is given 0.57 percent

now let us calculate this for sample

total population by adding the. all comes 3000

sickel cell people ,=17

percentage=(17/3000)×100

=0.56%

it is almost equal to the value for whole population.

u can test the hypothesis for other dusease traits also.the result will almost be the same.

ans 2..observed value for disease traits..=6 %

expected value..

.add diseased people= 192

percentage=(192/3000)×100

6.4 percent

it is somewhat fit for the observed value

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