1. Marfan syndrome follows a pattern of autosomal dominant inheritance. What is
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Question
1. Marfan syndrome follows a pattern of autosomal dominant inheritance. What is the chance that any child will inherit the dominant allele if one parent does not carry the allele and the other is heterozygous for it? Provide a clear explanation.2. Somatic cells of individuals with Down's syndrome usually have an extra chromosome 21; they contain 47 chromosomes. At which stage(s) of meiosis could a mistake alter the chromosome number?
3. What does it mean when an organism like Mendel's pea plants is true breeding? In one experiment, Mendel crossed a pea plant that bred true for green pods with one that bred true for yellow pods. All of the F1 plants had green pods. Which form of the trait (green or yellow pods) is dominant? Explain how you arrived at your conclusion.
4. What type of mutation has occurred in the DNA of people with sickle cell anemia? (Look back, if you need to, to see what causes sickle cell.)
5. The genetic makeup of an organism is called its ____, while the physical traits of an organism are called its ___.
Explanation / Answer
1. Marfan syndrome follows a pattern of autosomal dominant inheritance. What is the chance that any child will inherit the dominant allele if one parent does not carry the allele and the other is heterozygous for it? Provide a clear explanation.
Mm heterozygous X mm normal
gamtes M m m
Mm ,Mm ,mm , mm
50% 0f offspring are affected
2. Somatic cells of individuals with Down's syndrome usually have an extra chromosome 21; they contain 47 chromosomes. At which stage(s) of meiosis could a mistake alter the chromosome number?
NON DISJUNCTION AT MI OR MII STAGE OF MEIOSIS
NON DISJUNCTION AT POST MITOTIC CLEAVAGE
3. What does it mean when an organism like Mendel's pea plants is true breeding? In one experiment, Mendel crossed a pea plant that bred true for green pods with one that bred true for yellow pods. All of the F1 plants had green pods. Which form of the trait (green or yellow pods) is dominant? Explain how you arrived at your conclusion.
pea plant that bred true for green pods with one that bred true for yellow pods
GG green pods X gg yellow pods
gametes G g
offspring -------Gg
Gg green pods======F1 plants
so green trait is dominant
4. What type of mutation has occurred in the DNA of people with sickle cell anemia? (Look back, if you need to, to see what causes sickle cell.)
sickle cell anemia is point mutation in beta chain of hemoglobim
5. The genetic makeup of an organism is called its genotype , while the physical traits of an organism are called its phenotype
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