1. Mako is a mutagen that adds a methyl group to A nitrogenous bases, which caus
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Question
1. Mako is a mutagen that adds a methyl group to A nitrogenous bases, which causes those As to pair with G nitrogenous bases.
A)What kind of a base substitution does Mako promote?
B) So if this is your template strand following treatment with Mako, what would the daughter strand look like?
3’ AGCCTGACTGGAC 5’
2. OK, so think about this.... can a trisomic with a genotype of G/G/g ever produce a gamete of genotype g? Roughly what fraction/percent of all gametes would contain a g allele?
3. As the ozone layer thins/develops larger holes, human’s lifetime exposure to UV rays will also dramatically increase. How might increased UV exposure impact us from a genetics standpoint? Make sure you explain your answer. (2-3 sentences)
Explanation / Answer
1a. Mako promote transition base substitution mutation.
B. Daughter strand will look like
3'GGCCTGGCTGGGC5'
2. Generally trisomic human can't produce gamates. But in other species it surely can produce a gamates of genotype g. 30% of all allele contains a g allele.
3.UV is a mutagen that causes thymine-thymine dimers, which blocks the replication path and also leads to error prone replication that can effect to polypeptide and faulty protein synthesis that can ultimately leads to cancer.
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