Rate of drug self-administration is: a. a perfectly reliable and accurate measur
ID: 123536 • Letter: R
Question
Rate of drug self-administration is:
a. a perfectly reliable and accurate measure of a drug’s abuse liability.
b. an imperfect measure of the abuse liability of a drug because the motor effects of some readily abused drugs may interfere with an animal’s ability to produce an operant response.
c. an inaccurate measure of a drug’s abuse liability because all readily abused drugs are highly reinforcing, thereby producing a ceiling effect on operant responding.
d. inversely related to the abuse liability of a drug.
e. tremendously difficult to interpret, as a measure of the abuse liability of a drug, and is therefore rarely assessed in animal research.
Explanation / Answer
The answer is a. ..a perfectly reliable method.
FDA guidelines define abuse liability as the likelihood that a drug with psychoactive or CNS effects will sustain patterns of non medical self administration that result in disruptive or undesirable consequences.
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