PART 3. (4 Paints) Case study Gladys, an overweight 38 year-old one pack per day
ID: 123351 • Letter: P
Question
PART 3. (4 Paints) Case study Gladys, an overweight 38 year-old one pack per day smoker, is a restaurant manager who complains of gnawing pain that is moderately severe and almost always localized to the epigastrie region of her abdomen. Upon waking in the morning she is usually pain free, though by mid- to late-morning the ins to once again cause her discomfort. After eating lunch, her abdominal pain subsides but usually recurs again by wake her up during the night. After being examined by her primary care physician, she was referred to a gastroenterologist to undergo an endosco normal stomach anatomy but craters and inflammation were observed in the duodenum. Gastrie analysis demonstrated that the pH of the gastrie juice fell to 1.9 upon stimulation with gastrin and fasting serum gastrin levels were normal. mid-afternoon. Additionally, it is not uncommon for the pain and discomfort to pie evaluation. The upper GI endoscopy revealed Based on your understanding of the organization, function, and regulation of the GI tract, what is the most likely cause of Gladys' pain? Be as specific as possible. 1. 2. If fasting serum gastrin levels were elevated as a result of a gastrin-secreting tumor of the pancreas, what impact would this have on gastric acid secretion? 3. Discuss the role of Heliobacter pylori (H. pylori) in the development of gastric ulcers.Explanation / Answer
1.The above case is of Glady, 38 year old one pack per day smoker and restaurant manager by occupation. He comes with chief complain of epigastric pain that subsides after having lunch. Also endoscopy reveals craters and inflammation in duodenum.
From the following information the diagnosis clearly points towards that of duodenal ulcer as the pain of ulcer subsides after a meal. Also craters and inflammation in duodenum is indicative of ulcer.
2. The secretion of gastric acid is affected by the level of gastric that is evident through gastric serum levels. Increased secretion of gastric due to increased levels secreted by a gastric secreting tumour is common.
3.H.pylori is a common and known cause of gastric ulcers since a very long time. These spiral shaped pathogens are gram negative and reside in the gastric mucosa of most of the individuals. After successful colonization survival in the acidic stomach and tissue damage by toxin release plays a significant role in the development of the gastric ulcer. As acid secretion is inhibited due to the toxins released by the h. Pylori it leads to further increase in infection.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.