Mark each statement below TRUE or FALSE and give reasons. Credit given ONLY if y

Question

Mark each statement below TRUE or FALSE and give reasons. Credit given ONLY if your reasoning is correct. a. Gluconeogenesis is upregulated during long periods of exercise because blood [glucose] decrease. b. A mutation in Adenylate Cyclase would most likely decrease the rate of Gluconeogenesis in liver. c. Taking a drug that inhibits muscle lactate dehydrogenase would have no effect on ATP production under anaerobic conditions (ex: during intense exercise) d. A mutation in PFK-1 that reduces its affinity for ATP would always result in an increase in glycolysis e. Forcing the expression of Glucose-6-Phosphatase would raise blood glucose levels when fasting.

Explanation / Answer

a) the statement "gluconeogenesis is upregulated during long periods of exercise because blood glucose decreases" is True. when the body exercise for a long time, it requires energy. The energy is producing by the way of utilizing glucose and it results in decrease in glucose level in blood. It can automatically upregulate the production of glucose, the process is called gluconeogenesis.

e) Forcing the expression of Glucose 6phosphatase would raise blood glucose levels when fasting is True. When the expression of enzyme glucose 6 phosphatase increase, the conversion of glucose 6 phosphate in to free glucose increases. As a result, the total blood glucose level increases.

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