Two mice were treated with Busulfan A that kills spermatogenic cells. The semini

Question

Two mice were treated with Busulfan A that kills spermatogenic cells. The seminiferous tubules of one mouse were transplanted with spermatogonia and the status of spermatogenesis was examined in both mice one month later. What is the most likely outcome of this experiment?  

   A.   Both mice will have re-established spermatogenesis.

   B.   Neither mouse will have re-established spermatogenesis.

   C.   Only the mouse that did not receive spermatogonia will re-establish spermatogenesis.

   D.   Only the mouse that received spermatogonia will re-establish spermatogenesis.

The switch from mitosis to meiosis in spermatogenesis is regulated by _____ levels of _______ and this is induced by _________. Fill in the blanks.

   A.   low, glial cell derived neurotrophic factor (GDNF), follicle stimulating hormone (FSH)

   B.   high, glial cell derived neurotrophic factor (GDNF), luteinizing hormone (LH)

   C.   low, glial cell derived neurotrophic factor (GDNF), luteinizing hormone (LH)

   D. low, testosterone, follicle stimulating hormone (FSH)

The Tasmanian devil, Sarcophilus harrissi, has 14 chromosomes. If nondisjunction of chromosome 5 occurs in meiosis I, which of the following best describes the n of the resulting gametes?

   A.   All germ cells will be n=7

   B.   All germ cells will be n=5

   C.   Two germ cells will be n=14 and two will be n=7

   D.   Two germ cells will be n=8 and two will be n=6

Explanation / Answer

1) Busulphan A is a drug that causes depletion of male germ cells. The drug kills spermatogenic cells. Therefore, if seminiferous tubules are transplanted along with spermatogonia, the transplanted mouse will re-establish spermatogenesis. (option D).

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