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The questions below once, more than once, refer to the following term may be use

ID: 93030 • Letter: T

Question

The questions below once, more than once, refer to the following term may be used once, more than once, or all. A) Enhancer B.) Promoter C) Activator D.) Repressor E.) Terminator Can inhibit transcription of positively archiving any factors by blocking the binding site in Site in the DNA that that transcription initiation to the DNA. may be located far from The phenomenon in which RNA molecules destroyed if they have a sequence complementary to an introduced double-stranded is called: A) RNA interference B.) RNA obstruction C.) RNA, blocking D.) RNA targeting E.) RNA disposal of cells? In eukaryotes, why are certain genes expressed only in certain types eukaryote a) Different cell types contain different genes promoters b) Different cell same different enhancers e) Different cell types have same genes but different factors. d) Different cell types have different regulatory transcription The following is/are way(s) of controlling the efficiency of translation. a) Binding of repressor molecule to the mRNA. b) Binding of small molecules to the mRNA c) Binding of anti-sense RNA to the mRNA. d) Formation of polyribosome e) All of the above The following is an example of posttranslational of gene expression a) Control of transcription by repressor b) Control of transcription by an inducer c) Alternative splicing of RNA nucleus d) Controlling transport of mRNA from the e) Phosphorylation of protein A mutation can best be described as a: a) Change in cell morphology b) Change in number of the nucleus c) Transient change in DNA d) Permanent and inheritable change in DNA e) Change in protein conformation

Explanation / Answer

12. REPRESSOR inhibits transcription by blocking the binding of positively acting transcription factos to DNA.

Repressor decreases the rate of transcription.

Activator is any agent that regulates transcription of gene by increasing the rate of transcription.

Promoter is the region near the transcription initiation site where RNA polymerase binds.

Terminator occurs at the end of the gene or operon tha cause the transcription to stop.

Thus the answer is repressor.

13. The site in the DNA located far from the site of transcription initiation in any directiopn is ENHANCER.

These are located upstream or downstream or several thousand nucleotides far away from the initiation site within the coding region. WHen the DNA binding protein attached to the enhancer, conformational change occurs in the DNA which allows the interaction between activators and transcription factors to occur.

Other regions such as promoter, activator and repressor are al located near the site of initiation.

14.The phenomenon in which RNA moleculaes are destroyed if ds RNA molecules with complementary squence are introduced is called RNA INTERFERENCE

It is a post transcriptional process. It is triggered by the introduction of ds RNA. Once activated it leads to gene silencing in a sequence specific manner..

15. In eukaryotes certain genes are expressed in only certain cell types due to the presence of set of regulatory transcription factors found in the part of the cell.

Different cell types can have different genes or promoters or enhancers , it is the presence of regulatory transcription factors that decide the expression of the genes according to the need of the cell.

17. Example for post translational gene expression is PHOSPHORYLATION.

Protein activity formed after translation can be altered by addition of a phospahte group to the protein by specific enzymes called kinases.This process is called phophorylation.

18. Mutation are permanent and inheritable changes that takes place in the DNA.

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