7. Diffusion\" sounds slow, but on the scale of a cell it is very fast. The aver
ID: 88580 • Letter: 7
Question
7. Diffusion" sounds slow, but on the scale of a cell it is very fast. The average instantaneous velocity of a particle in solution is v (kTim) k, where k 1.38 x 1016 cm K in K, in g/molecule. A) calculate the approximate time it would take a molecule of glucose and a molecule of lactate dehydrogenase protein), each moving linearly average instantaneous velocity at 370C, to travel 20 um (an approximate width for a mammalian cell [molecular mass for glucose 180 g/mol; molecular mass for lactate g/mol.Explanation / Answer
3. Use arithmetic to determine the chain lenghth of palmitate with the given value of one methylene unit.
(16 CH2) (0.13nm 1CH2) = 2.1nm
4. A)The hydrophobic effect represents the tendency of water to exclude non-polar molecules. The effect originates from the disruption of highly dynamic hydrogen bonds between molecules of liquid water. Polar chemical groups, such as OH group in methanol do not cause the hydrophobic effect. So from what i can see is compound ! had more -OH groups so its negative hydrophotobicity value of compund 2 is more.
B)
the increase in pH from 2 to 7 is increases the relative hydrophobicity of Orn, Lys, His, and Arg, likely to partial (Orn, Lys, Arg) or complete (His) deprotonation of these residues at the higher pH value, i.e., the positive charge on these side chains is diminished or eliminated or an increased neutralization of the positive charge by the increased concentration of the anions H2PO4 and HPO24 is occurring as the pH is increased from 2 to 7. In contrast, the relative hydrophobicities of the acidic side chains of Asp and Glu are decreasing with an increase in pH, due to deprotonation of these residues at pH 7 (the pKa of these side chains is ~4.0), i.e., they become negatively charged so energy change is also observed.The mobility of water molecules in the "cage" (or solvation shell) is strongly restricted. This leads to significant losses in translational and rotational entropy of water molecules and makes the process unfavorable in terms of free energy of the system.
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