The adenine nucleotide translocase (ADP-ATP translocase), a transporter located

Question

The adenine nucleotide translocase (ADP-ATP translocase), a transporter located in the inner mitochondrial membrane, transports ADP and ATP across the membrane. It is an antiporter. (Recall that these adenine nucleotides are negatively charged: ADP3- and ATP4-.) Answer parts (a), (b), and (c), below. (a) Which direction is ATP4- transported during times of active oxidative phnsphnrylation? out of the mitochondria! matrix into the mitochondria! matrix there is no net flow of ATP4- (b) What drives the transport of adenine nucleotides? transport is coupled with ATP hydrolysis simple diffusion the electrochemical gradient (membrane potential) (c) What is the ratio of ADP to ATP transported by the adenine nucleotide translocase? That is, how many ADP are transported for each ATP transported? 3 ADP : 4 ATP 4 ADP : 3 ATP 1 ADP : 1 ATP 2 ADP : 3 ATP

Explanation / Answer

a) into the mitochondrial matrix

b) the electrochemical gradient (membrane potential)

c) 1 ADP : 1 ATP

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