At a high concentration subunits tubulin mRNA: a) decrease b) increases c) remai

Question

At a high concentration subunits tubulin mRNA: a) decrease b) increases c) remains unchanged Methylation of DNA ____p gene expression. a) increases b) decreases c) does not change Human gena therapy in the treatment of severe combined immunodeficiency (SCID) did NOT involve: a) use of a modified retrovirus as vector b) injecting the virus carrying the ADA gene directly into the patient c) use of tissue culture Enhancer elements: a) can be located downstream from the promoter b) function in only one orientation c) are located within 200 from the TATA box d) are the same as a GC box Which of the following is true? a) Silencers are protein that bind to enhancer DNA sequences. B) Activators are protein that bind to enhancer DNA sequences. Enhancers are protein that bind to activator DNA sequences. d) A repressor is a DNA sequence, NOT a protein A promoter ___ a cis-acting site: a) is b) is not If a wild type E. coli strain is grown in the presence of lactose, the operon will be: a) transcribed b) NOT transcribed

Explanation / Answer

10) c DNA methylation occurs on the cytosine bases of DNA, forming 5-methylcytosine by DNA methyltransferase (DNMT) enzymes. The altered cytosine residues are usually immediately adjacent to a guanine nucleotide, resulting in two methylated cytosine residues sitting diagonally to each other on opposing DNA strands. This is a tool for controlling gene expression and involved in reducing expression of altered genes in tumours

11)a

Modified retroviruses have been used in gene therapy. Tissue culture with ADA genes has not successfully been done. Viruses with ADA genes have also been used

13 b enhancer is a DNA region binds activators to increase the likelihood that transcription of a particular gene will occur

14 a) is Promoters are relatively short sequences of DNA, approximately 40 base pairs (bp), usually located upstream of a transcription start site. These are cis regulatory sirs

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