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Edward who is phenotypically noir all has a sister with cystic fivrosis. He is e

ID: 82917 • Letter: E

Question

Edward who is phenotypically noir all has a sister with cystic fivrosis. He is expecting a child with Jennifer whose family history is unknown. Neither of his parents have CF aka phenotypically normal.
Write each persons genotype using A has normal and a forthw autosomal recessive duisease.
What is the probability that Edward is heterozygous for CF gene. Explain
If the frequency of heterozygous in general population is 1/30 what is the probability the child will have CF
Edward who is phenotypically noir all has a sister with cystic fivrosis. He is expecting a child with Jennifer whose family history is unknown. Neither of his parents have CF aka phenotypically normal.
Write each persons genotype using A has normal and a forthw autosomal recessive duisease.
What is the probability that Edward is heterozygous for CF gene. Explain
If the frequency of heterozygous in general population is 1/30 what is the probability the child will have CF

Write each persons genotype using A has normal and a forthw autosomal recessive duisease.
What is the probability that Edward is heterozygous for CF gene. Explain
If the frequency of heterozygous in general population is 1/30 what is the probability the child will have CF

Explanation / Answer

If the frequency of heterozygous in general population is 1/30 what is the probability the child will have CF

Normal allele----------A

Abnormal allele----------a

Genotype

Aa

Heterozygous

normal

AA

Homozygous

normal

aa

Homozygous

affected

If the frequency of heterozygous in general population is 1/30 what is the probability the child will have CF

=1/30x1/30 = the probability of both being carriers.

If they're both carriers then each child faces a 1/2 chance of being carriers or inheriting the illness= 1/4.

= 1/2 x 1/30 x 1/30= CARRIERS= 1/1800.

THOSE HAVING THE DISEASE THOUGH WOULD BE= 1/4 x 1/30 x 1/30= 1/3600

Write each persons genotype using A has normal and a for the autosomal recessive duisease.

What is the probability that Edward is heterozygous for CF gene. Explain

Aa     x Aa

AA

Aa

Aa

aa

Edward is heterozygous for CF gene. =1/2 --answer

Genotype

Aa

Heterozygous

normal

AA

Homozygous

normal

aa

Homozygous

affected

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