Gluconeogenesis is the of glucose from non-carbohydrate sources. A diagram of gy

Question

Gluconeogenesis is the of glucose from non-carbohydrate sources. A diagram of gycolsis and gluconeogenesis is provided below glucose Which of the following substances can serve as a carbon source for gluconeogenesis? Check all that apply. ADP glucose 6-phosphate fumarate lysine tyrosine fructose-6-phosphate ATP lactate ADP l j pyruvate fructase-1,6-bisphosphate oxaloacetate myristic acid dihydroxyacetone s glyceraldehyde 3-phosphate phosphate NAD Pi NAD++ Pi NADH H+ NADH H 1,3-bisphosphoglycerate ADP ADP ATP ATP 3-phosphoglycerate

Explanation / Answer

The following will can serve as source of carbon in gluconeogenesis

Lactate (main source)

Oxaloacetate (obtained from lactate)

Pyruvate (this get converted to glucose finally)

Tyrosine ( both glucogenic and ketogenic amino acid)

Fumarate

NOTE:

Lysine cannot be used as it is only ketongenic

Myrisitic acid : It is even numbered fatty acid and it is proved that odd numbered fatty acids are involved in gluconeogensis

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