You are working with two inbred strains of mice that are homozygous for the H-2

Question

You are working with two inbred strains of mice that are homozygous for the H-2 locus. One strain homozygous for the H-2k locus. One strain is homozygous for the H-2k haplotype while the other strain is homozygous for the H-2d haplotype. You isolate APC's and T cells from both stain and treat the APC's with a foregin antigen. According to the two-recpetor model, which combiantion of APC's and T-cells should result in an immune response? Select all of the below comination that apply.

A) H-2k APC mixed with H-2k Tcells

B) H-2k APC mixed with H-2d Tcells

C)H-2d APC mixed with H-2d Tcells

D)H-2d APC mixed with H-2k Tcells

E)H-2k APC mixed with H-2k/H-2d fused Tcells

Explanation / Answer

Option E is the right answer

Because of the both strain produces antigens and these are casues immune response and activation of T cells and APC.

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