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I got some questions I need some help with. I had started but I feels that I am

ID: 794593 • Letter: I

Question

I got some questions I need some help with. I had started but I feels that I am a little bit struck and would be glad if you can help me with the answers and also some explanation why.

Busulfan (figure below) is a di-ester out of 1,4 butanediol with Methanesulfonic acid

Busulfan

Busulfan can be more water soluble if it can create a complex with BCD(Figure below)

BCD

The figure shows that BCD has to carbohydrate tails that are connected with a heterocyclic carbon compound.

Part 1. Which of these two components in BCD can be expected to increase the water soluble?

I guess it is the OH-group according to the

Explanation / Answer

i guess the answer for part 1 is N-H group

for 2nd part i think it is the hydrogen bonding between them

for 3 rd part it will form a cyclic ether with five membered ring with oxygen in the ring