Figure 1 shows that intracellular signaling pathways can be highly interconnecte

ID: 79023 • Letter: F

Question

Figure 1 shows that intracellular signaling pathways can be highly interconnected.

From the information in Figure 1, which of the following statements is incorrect?

(a) The GPCR and the RTK both activate phospholipase C.

(b) Activation of either the GPCR or the RTK will lead to activation of transcriptional regulators.

(d) Ras is activated only when the RTK is active and not when the GPCR is active.

signal molecule signal molecule activated GPCR G protei G protei phospholipase Ras-GEF (Sos) diacylglycerol adenylyl oydase MAP kinase kinase kinase cyclic AMP protein kinase calmodulin kinase CaM kinase PKC MAP kinase transcriptional regulators other effector p

Explanation / Answer

From the information in Figure given the following statements is incorrect:

c) CaM-kinase is only activated when the GPCR is active and not when the RTK is active is wrong as both of these pathways are interlinked.

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Figure 1 shows that intracellular signaling pathways can be highly interconnecte

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