Two friends go for a swim in Tasman Sea in the South Pacific Ocean. While swimmi

Question

Two friends go for a swim in Tasman Sea in the South Pacific Ocean. While swimming they both get stung by Box Jellyfish. One of them dies immediately but other one survives with minor injuries. It's a new species of Box Jellyfish and the venom is yet to be identified, though it is speculated to belong to the same class of venoms from other species of Box Jellyfish. The venom from other Box Jellyfish includes a molecule that binds irreversibly to neuronal GABA receptors. Typically, GABA receptors are opened by benzodiazepines, which allow chloride ions into the cell. The Jellyfish venom disables chloride channels, and thus prevents transmission of neural messages. a) Why does the venom affect one person and not the other? b) What is the molecular target of this new venom? c) What methods could be used to treat the victim or prevent poisoning by Box Jellyfish? Give detailed experimental design.

Explanation / Answer

answers :

a) Because same class of venom from other species of Box jellyfish

b) Molecular target for new venom is which binds irreversibly to neuronal GABA receptor

c) Jellyfish venom disables chloride channels and thus prevents transmission of neural message

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