Scenario 1: A mouse deficient in ghrelin is sewn together with a wild-type (cont
ID: 77993 • Letter: S
Question
Scenario 1: A mouse deficient in ghrelin is sewn together with a wild-type (control) mouse in a parabiotic experiment.
2. What will eventually happen to the ghrelin-deficient mouse under this condition? (2 points)
A.Food intake will increase and the mouse will gain weight.
B.Food intake will decrease and the mouse will lose weight.
C. Food intake will not change and the mouse will not change weight.
Scenario 2: A mouse deficient in the ghrelin receptor is sewn together with a wild-type (control) mouse in a parabiotic experiment.
3. What will eventually happen to the ghrelin receptor-deficient mouse under this condition? (2 points)
A. Food intake will increase and the mouse will gain weight.
B. Food intake will decrease and the mouse will lose weight.
C. Food intake will not change and the mouse will not change weight.
4. What will eventually happen to the wild-type (control) mouse under this condition? (2 points)
A. Food intake will increase and the mouse will gain weight.
B. Food intake will decrease and the mouse will lose weight.
C. Food intake will not change and the mouse will not change weight.
Scenario 3: A mouse deficient in deficient in ghrelin is sewn together with a mouse deficient in the ghrelin receptor in a parabiotic experiment.
5. What will eventually happen to the ghrelin-deficient mouse under this condition? (2 points)
A. Food intake will increase and the mouse will gain weight.
B. Food intake will decrease and the mouse will lose weight.
C. Food intake will not change and the mouse will not change weight.
6. What will eventually happen to the ghrelin receptor-deficient mouse under this condition? (2 points)
A. Food intake will increase and the mouse will gain weight.
B. Food intake will decrease and the mouse will lose weight.
C. Food intake will not change and the mouse will not change weight.
IPHY 4440 2
Explanation / Answer
Senario 1:
1. The food intake will increase and the mouse will gain weight as the control mouse provides the ghrelin needed for the deficit mouse.
Senario2:
2. The food intake will not change and the mouse will not change weight in the ghrelin receptor-deficient mouse as the ghrelin receptor deficient mouse cannot metabolise the ghrelin.
3. In wild-type the food intake will increase and the mouse will gain weight because of the presence of high amount of ghrelin.
Senario 3:
5. In this senario the food intake will increase in the ghrelin-deficient mouse as the ghrelin will be provided by the other. The food intake of ghrelin receptor-deficient mouse will not change and the mouse will not change weight as the mouse cannot metabolise ghrelin.
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