2. Immune checkpoint inhibition strategies to treat cancer involves: a. Blocking

Question

2. Immune checkpoint inhibition strategies to treat cancer involves:

a. Blocking the ligand on the tumor cell that attaches to the regulatory T-cell

b. Blocking the ligand on the regulatory T-cell that attaches to the tumor cell

c. Both A and B

(***Please explain why?)

2. All of the following characteristics describe randomized clinical trials EXCEPT?

a. Test one new therapy per trial

b. Allow participation only to a pre-defined subset of patients

c. Use traditional statistical approaches

d. Allow rolling modification of the study design as the study progresses

(***Please explain why?)

Explanation / Answer

2. b. Blocking the ligand on the regulatory T-cell that attaches to the tumour cell

Immune checkpoint inhibition strategies (may be inhibitory or stimulatory). Blockade of Immune checkpoint inhibitions activates immune functioning. Blocking the ligand on the regulatory T-cell allow the immune cell to attack the tumour cell.

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