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A cell expresses a transmembrane protein that is cleaved at the plasma membrane

ID: 62064 • Letter: A

Question

A cell expresses a transmembrane protein that is cleaved at the plasma membrane to release an extracellular fragment. The fragment binds to receptor proteins on nearby cells and activates signaling pathways resulting in altered gene expression patterns in the cells. What form of intercellular signaling does this represent?

Contact-dependent signaling

Paracrine signaling

Endocrine signaling

Autocrine signaling

(A)

Contact-dependent signaling

(B)

Paracrine signaling

(C)

Endocrine signaling

(D)

Autocrine signaling

Explanation / Answer

Ans- paracrine signaling

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