1. Although both NAD+ and FAD are coenzymes for dehydrogenase enzymes, they are
ID: 61437 • Letter: 1
Question
1. Although both NAD+ and FAD are coenzymes for dehydrogenase enzymes, they are not interchangeable. Suggest two reasons for why they cannot be interchanged even though they have very similar functions.
ingrediens Com,sugar, mlil tamhi pyridasinet hnstrac lande B. BHT aded to Ingredients: Corn, sugar, malt flavoring, corn syrup. Vitamins and minerals ascorbic acid, iron, zinc, niacinamide, pyridoxine hydrochloride, riboflavin, vitamin A palmitate, thiamine hydrochloride, folic acid, vitamin D, BHT added to packaging to maintain qualityExplanation / Answer
1.
A coenzyme is a small molecule which in combination with an enzyme promotes the enzyme activity. The coenzyme is a cofactor, which is loosely bound to the enzyme when compared to regular cofactor. In presence of coenzyme, the enzyme activity takes place instantaneously. Examples: NAD+, FAD, biotin, and lipoamide.
Nicotinamide adenine dinucleotide and Flavin adenine dinucleotide (FAD) are the coenzymes that are present in living systems. Its oxidized form is NAD+ (oxidising agent, can accept electrons) and reduced form is NADH. NAD is involved in redox reactions and carries electrons from one reaction to another.
FAD is a derivative of the vitamin riboflavin whose reactive part is isoalloxazine ring. FAD and NAD+ both can accept two electrons, while in doing so, unlike NAD+, FAD takes up two protons.
The NAD is reduced by accepting single hydrogen (H) from hydrogen atom (H2), while FAD is reduced by accepting full hydrogen atom. Thus, an electron pair from the hydrogen atom (H2) and the other hydrogen is freed into the medium by the NAD. Hence their reduced forms are written as (NADH + H+) and FADH2.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.