A woman is heteroplasmic for a severe condition that significantly impacts the q

Question

A woman is heteroplasmic for a severe condition that significantly impacts the quality of her life. Coincidentally, her husband's mother was also heteroplasmic for the same condition. Which of the following are true (pick one):

-If the couple conceives a child "naturally", this first child will definitely inherit this condition.

-If the couple uses a sperm donor with no history of this condition, they are certain to produce a child without the condition.

-If the couple uses an egg donor with no history of this condition, they are certain to produce a child without the condition.

-If the couple conceives a child "naturally", this first child will definitely not inherit this condition.

-If the couple conceives a child through in vitro fertilization using an egg and sperm harvested from the couple, this first child will definitely inherit this condition.

-If the couple conceives a child "naturally" that does not have the condition, they can be sure that their second child will not have the condition either.

Explanation / Answer

-If the couple conceives a child "naturally", this first child will definitely inherit this condition.

-If the couple uses an egg donor with no history of this condition, they are certain to produce a child without the condition.

-If the couple conceives a child through in vitro fertilization using an egg and sperm harvested from the couple, this first child will definitely inherit this condition.

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