1. To monitor a patient with impaired renal function, the most useful serial ser
ID: 55590 • Letter: 1
Question
1. To monitor a patient with impaired renal function, the most useful serial serum determination is:
a. creatine
b. creatinine
c. BUN
d. Uric acid
e. Total nonprotein nitrogen
2. What is the purpose of the 8-hydroxyquinoline in the cresolpthalein determination for calcium?
A) Color reagent
B) Reduce Mg interference
C) Produce an alkaline pH
D) Produce an acid pH
3. Aldosterone acts on the distal tubule to:
a. Increase potassium reabsorption and sodium excretion
b. Decrease sodium reabsorption and increase potassium excretion
c. Increase sodium reabsorption and decrease potassium excretion
d. Increase sodium reabsorption and potassium excretion
Please explain answers
Explanation / Answer
1. b. Creatinine and c. BUN are useful in determining the kidney disease. Creatinine is a metabolic waste product produced at the end of the muscle metabolism of creatine. Most of the creatinine formed during the product are excreted through the kidneys. Similarly Blood urea nitrogen is the by product of protein metabolism. It is a toxic chemical so it is excreted by the kidneys. If the kidneys are impaired the excretion of these two metabolic products are diminished leading to the high levels of these compounds in blood, makes them to identify as biomarker for kidney disease.
2. 8-hydroxyquinoline reduce magnesium interference in determination of calcium. It acts as a chelator and forms a complex with magnesium as a precipitate.
3. Aldosterone increase sodium reaborption and potassium excretion. When the body needs to save the salt and water the aldosterone will act on the receptors of renal tubules, activating ion channels. The activated ion channels will increase the sodium reabsorption and potassium excretion from urine.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.