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1. A homologous series of primary alcohols is to be determined by GC. Given that

ID: 505624 • Letter: 1

Question

1. A homologous series of primary alcohols is to be determined by GC. Given that the retention time for ethanol is 1 min, predict the retention times for 1-propanol, 1-butanol, and 1-pentanol.

2. Which type of column would you recommend for the separation of the alcohols in Question 1?

3. List several factors that affect resolution and describe how they can be controlled.

4. What length of column would be required to just resolve two peaks with retention times of 92 and 107 s, respectively, using a column with an H of 1.60 cm/plate?

Explanation / Answer

Ans 1. The gas chromatography or GC is a technique to seperate individual components from a mixture depending on their affinity towards polar stationary phase.

The retention time of 1 propanol will be 2.05 min, of 1 butanol will be 4.33 min and of 1 pentanol will be 8.28 min.