What is the order of decreasing reactivity towards nucleophilic acyl substitutio

Question

What is the order of decreasing reactivity towards nucleophilic acyl substitution for the carboxylic acid derivatives? (most reactive first). a. I, II, III, IV b. II, III, I, IV c. III, II, I, IV d. IV, I, III, II Consider the reaction below to answer the following questions: This reaction is an example of: a. an intermolecular nucleophilic acyl substitution reaction b. an intramolecular nucleophilic acyl substitution reaction c. an intermolecular S_N 2 reaction d. an intramolecular S_N 2 reaction

Explanation / Answer

3.

Cl- is good leaving group followed by acyl group, followed by alkoxide and amide.

so answer is option d.

4.

The above reaction is an example of inter-molecular SN2 reaction.

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