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ID: 489753 • Letter: I

Question

I asked this question already but I want a second opinion Please and Thank you so much.

Arrange in order the events that occur in the production of a fever of 39.4 C(103 F) and recovery from this state.

A. 39.4 C (103 F) temperature is reached and maintained.

B. Prostaglandins(PGs) cause the hypothalamic "thermostat " to be reset from normal.

C. Vasoconstriction and shivering occur as heat is conserved in order to raise body temperature to the 39.4 C(103 F) lever directed by the hypothalamus.

D. Source of pyrogens is removed (for example, bacteria are killed by antibiotics), lowering hypothalamic "thermostat" to 37.5 C(98.6 F)

E. "Crisis" occurs. Obeying hypothalamic order, the body shifts to heat loss mechanisms such as sweating and vasodilation, returning body temperature to normal.

F. Infectious organisms cause phagocytes to release interleukin-1, which then causes hypothalamic release of PGs

Explanation / Answer

Fever occurs primarily in response to an infection which causes an increase in the body temperature, i.e causes the 'thermostat' to reset. As a consequence, blood begins to flow to the core of the body causing a drop in the surface temperature inducing shivering. Antibiotics administered kill the bacteria and bring down the body temperature. Heat is released which causes sweating returning the body temperature to a normal value. The sequence of events can be arranged as follows:

F. Infectious organisms cause phagocytes to release interleukin-1, which then causes hypothalamic release of PGs

B. Prostaglandins(PGs) cause the hypothalamic "thermostat " to be reset from normal.

C. Vasoconstriction and shivering occur as heat is conserved in order to raise body temperature to the 39.4 C(103 F) lever directed by the hypothalamus.

A. 39.4 C (103 F) temperature is reached and maintained.

D. Source of pyrogens is removed (for example, bacteria are killed by antibiotics), lowering hypothalamic "thermostat" to 37.5 C(98.6 F)

E. "Crisis" occurs. Obeying hypothalamic order, the body shifts to heat loss mechanisms such as sweating and vasodilation, returning body temperature to normal.

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